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The deadly disease that can affect humans years before the unwanted host of its host is to target Dundy University experts.
Up to seven million people all over the world suffer from Chagas disease, a parasitic disease that is still not discovered for decades before causing severe symptoms and sudden death.
Despite the spread of this condition, and with 75 million people at risk of infection, current treatments are limited in the event and come with significant side effects.
To try to address this unparalleled need, experts in the university’s drug detection unit obtained funding from the Medical Research Council to develop a pre -clinical candidate that could lead to new treatments and treatments.
“Chagas disease is particularly sad, and it lives within its human host, which is often completely aware of it until it is too late,” he said. Dr. Mano de ReckerThe head of the pathogenic biology within the College of Life Sciences in Dandy.
“The current treatments remain very bad, require that they are taken over a period of 60 days, and can have significant side effects, including rash, nausea, diarrhea, weight loss and neurological issues.
“Doctors do not like to prescribe them and patients do not like to take them, so it is clear that new treatments are needed.
However, the discovery of drugs is a long and complex process.
“Here in Dunde, we have made great progress in recent years to learn how to develop treatments for Chagas, and this knowledge will be decisive with the start of this new research.
“Our intention is to determine the pre -clinical candidate – a molecule with the ability to enter into human experiments – which we hope will form the basis of new treatments that will help alleviate the suffering caused by the Chagas disease with some of the poorest population in the world.”
Once it only found inside Central and South America, Chagas disease slowly began to get a foothold around the world due to the large -scale population movements.
It is spread by triple insects, which usually live in the walls or roofs of homes that have been created poorly.
They wake up at night, bite the exposed skin areas and defecate them close.
The infection spreads when a person unintentionally distort the stool in the open wound, or his eyes or mouth.
It can then spread by blood transfusion and from the mother to the child.
Moving orally, due to the unintended consumption of insects, for example in unpasteurized juices, is also common.
Chagas disease reports in the UK are rare due to the lack of testing and public awareness, but there are likely to be thousands of cases in the country from those who were injured elsewhere.
The World Health Organization estimates that Six and seven million people Throughout the world, the Tribangoma Cruisse affects the parasite that causes Chagas disease, which led to 12,000 deaths every year.
Dr. De Recker added: “The general public may consider Scotland an unlikely place to develop a pre -clinical candidate for a tropical situation, but we are known all over the world as leaders in this field.
“While she started making her presence out of its traditional stronghold in the Americas, the spread of Chagas disease is still slow.
“However, it is a disease that may become increasingly prevalent in the coming decades and there is still an urgent need to help those people who have already been affected or live under its shadow.”
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